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Accordingly, we speculate that the disruption of glutamine-glutamate metabolism and subsequent impaired GSH metabolism might be the metabolic factors underlying JEV-induced neuronal damage and the progression of JE

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The third pathway, the ceramide pathway, is triggered by radiation-induced activation of acid sphingomyelinase in the plasma membrane, producing ceramide via hydrolysis of sphingomyelin

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Declining IgG levels suggest successful immunosuppression, while persistently high levels may indicate sub-optimal therapy or ongoing inflammation, necessitating treatment adjustments [50]

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Standard treatments or low vision rehabilitation more appropriate

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These findings implied that GBDP, when utilized alongside conventional therapy, effectively alleviates angina symptoms, improves quality of life, and may contribute to a reduction in depressive symptoms among patients with SAP (70)

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